Neauvia Organic Stimulate (1ML)

NEAUVIA™ Organic Stimulate Overview

NEAUVIA™ Organic Stimulate is a unique dermal filler that not only provides volumization but also stimulates collagen production. It contains 26 mg/ml of Hyaluronic Acid (HA) and 1% calcium hydroxyapatite (CaHA), which plays a critical role in stimulating neocollagenesis. This product is designed for patients who need volume restoration along with the long-term benefits of skin quality improvement through collagen stimulation.

Indications for Use of NEAUVIA™ Organic Stimulate

NEAUVIA™ Organic Stimulate is particularly suited for addressing both volume loss and skin rejuvenation. Its primary uses include:

• Deep Tissue Restoration: For treating deep wrinkles and folds such as nasolabial folds.
• Volume Enhancement: Corrects volume loss in areas such as the cheeks, chin, and jawline.
• Biostimulation: Enhances skin texture, elasticity, and firmness by stimulating natural collagen production.

This product is a popular choice among patients seeking both immediate results and long-term skin improvement.

Dosage and Administration of NEAUVIA™ Organic Stimulate

Each syringe of NEAUVIA™ Organic Stimulate contains 1 ml of the product, consisting of 26 mg/ml of hyaluronic acid and 1% calcium hydroxyapatite. The filler is injected into the deep dermal layers or subcutaneous tissue to achieve optimal volume restoration and skin biostimulation.

• Concentration: 26 mg/ml of HA, cross-linked with PEG, and 1% CaHA.
• Recommended Volume: 1 ml per treatment session, though this can vary depending on the area treated.
• Injection Depth: This filler is typically injected into the deep dermis or subcutaneous tissue for effective volumization and collagen stimulation.

The presence of calcium hydroxyapatite ensures that the collagen-stimulating effect will last beyond the typical filler results, with improvements visible for up to 12 months.

Side Effects and Precautions

NEAUVIA™ Organic Stimulate is a safe product, but like any injectable treatment, it can cause mild side effects. Most side effects are temporary and resolve within a few days.

• Common Side Effects:
  • Swelling and redness at the injection site.
  • Bruising and tenderness in the treated area.
• Severe Side Effects (rare):
  • Vascular Occlusion: If the filler is injected into a blood vessel, it could lead to tissue ischemia or necrosis.
  • Allergic Reactions: Some patients may experience hypersensitivity to the ingredients, though this is rare.

Patients with a history of autoimmune conditions or severe allergies should inform their healthcare provider before treatment. Pregnant or breastfeeding women are advised against using this product.

Clinical Studies and Real-World Outcomes

Clinical studies and real-world data show that NEAUVIA™ Organic Stimulate provides both immediate volumizing effects and long-term skin improvements, thanks to its collagen-stimulating properties.

• Collagen Production: The calcium hydroxyapatite content stimulates fibroblasts to produce collagen, elastin, and glycosaminoglycans over time.
• Volume Restoration: Patients report immediate improvement in facial volume, particularly in areas such as the cheeks and jawline.
• Long-Term Results: The combination of HA and CaHA provides results that last for 9-12 months, with continued improvement in skin quality.

The product is especially effective in improving skin density, elasticity, and overall skin texture.

Drug Interactions

While NEAUVIA™ Organic Stimulate is generally safe for most patients, there are some potential interactions with medications that may increase the risk of side effects:

• Anticoagulants: Patients on blood thinners such as aspirin or warfarin may experience increased bruising or bleeding.
• Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): These medications, like ibuprofen, may also increase the risk of bruising at the injection site.

Patients should discuss any ongoing medications with their healthcare provider to minimize the risk of complications.

Technology Behind NEAUVIA™ Organic Stimulate

NEAUVIA™ Organic Stimulate employs advanced PEG cross-linking technology and Bacillus Subtilis-derived hyaluronic acid, making it one of the most biocompatible and safe dermal fillers on the market.

• PEG Cross-Linking: This technology provides a 3D hydrogel matrix, ensuring that the product is non-toxic, degradable, and resistant to proteolytic enzymes, which leads to longer-lasting results.
• Calcium Hydroxyapatite (CaHA): The 1% CaHA stimulates neocollagenesis, providing long-term skin improvement beyond the initial volume restoration.
• Bacillus Subtilis Hyaluronic Acid: Unlike HA derived from Streptococcus bacteria, Bacillus Subtilis HA is free from endotoxins, proteins, and bacterial contaminants, ensuring the highest level of safety and purity.

This combination of technologies makes NEAUVIA™ Organic Stimulate highly effective for both volumization and skin biostimulation.

Post-Treatment Care

After receiving NEAUVIA™ Organic Stimulate injections, patients should follow these post-treatment care guidelines to optimize results and minimize side effects:

• Avoid Makeup: Patients should refrain from applying makeup to the treated area for at least 12-24 hours.
• Avoid Sun Exposure: Direct exposure to sunlight, UV lamps, and tanning beds should be avoided for at least two weeks.
• No Strenuous Activity: Limit physical activity and facial movements for 24-48 hours post-treatment to reduce swelling and bruising.

Patients should monitor the treated area and contact their healthcare provider if they experience any prolonged side effects or complications.